Role of neighborhood socio-structural factors on the tumor epigenome and racial disparities

Project summary

Where we live is important for health outcomes. Living in a neighborhood with more poverty, less green space, or more pollution disproportionately impacts Black women. Black women with ovarian cancer also have worse survival than White women. However, we do not fully understand how place influences survival among Black and White ovarian cancer patients. Aspects of our neighborhood, such as exposure to stressors and environmental toxins, may lead to biologic changes that directly impact cancer development and progression. This study will explore the interplay between neighborhood, tumor biology, and survival to understand inequities in ovarian cancer survival.