Palladium(0) and Juglone: a new alliance in the fight against ovarian cancer

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Giovanni Tonon; Nicola Demitri; Thomas Scattolin; Flavio Rizzolio; Fabiano Visentin

doi:10.1039/d5dt01792k

Palladium(0) and Juglone: a new alliance in the fight against ovarian cancer

Giovanni Tonon & Fabiano Visentin et al. · 2026-01-06

Four Juglone-based Pd(0) complexes with varied ligands were synthesized and characterized. They showed strong cytotoxicity and cancer selectivity. The most promising complex inhibited the PIN1 oncoprotein, as confirmed by Western Blot.

Palladium(0) and Juglone: a new alliance in the fight against ovarian cancer

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