Investigator
Beamline Scientist · Elettra Sincrotrone Trieste SCpA, Hard X-ray Diffraction Beamlines and Structural Biology Lab
Palladium(0) and Juglone: a new alliance in the fight against ovarian cancer
Four Juglone-based Pd(0) complexes with varied ligands were synthesized and characterized. They showed strong cytotoxicity and cancer selectivity. The most promising complex inhibited the PIN1 oncoprotein, as confirmed by Western Blot.
Unlocking the potential of organopalladium complexes for high-grade serous ovarian cancer therapy
High-Grade Serous Ovarian Cancer (HGSOC) is the most common and lethal subtype of ovarian cancer, known for its high aggressiveness and extensive genomic alterations.
Palladium(II)-Indenyl Complexes Bearing N-Heterocyclic Carbene (NHC) Ligands as Potent and Selective Metallodrugs toward High-Grade Serous Ovarian Cancer Models
In this study, we synthesized novel Pd(II)-indenyl complexes using various
Beamline Scientist
Elettra Sincrotrone Trieste SCpA · Hard X-ray Diffraction Beamlines and Structural Biology Lab
PhD - Doctoral School In Chemical and Pharmaceutical Sciences and Technologies
Università degli Studi di Trieste · Dipartimento di Scienze Chimiche
MSc Degree in Chemistry - 110/110 cum laude