Human tumor microenvironment chip evaluates the consequences of platelet extravasation and combinatorial antitumor-antiplatelet therapy in ovarian cancer
A tumor microenvironment chip reveals how platelets may fuel cancer metastasis and chemoresistance and unravels a new treatment.
Journal
Science AdvancesInstitutions
Authors
Funding
Cancer Center Support GrantCore 1: Pathology CoreAn artery-on-a-chip system containing blood outgrowth endothelium as a model of vaso-occlusion and drug testing in sickle cell diseasePlatelets promote growth of ovarian cancerHarnessing the power of exosomes for non-coding RNA deliveryNational Science Foundation Grant 1944322An artery-on-a-chip system containing blood outgrowth endothelium as a model of vaso-occlusion and drug testing in sickle cell diseaseCancer Center Support GrantCore 1: Pathology CorePlatelets promote growth of ovarian cancerHarnessing the power of exosomes for non-coding RNA deliveryAn artery-on-a-chip system containing blood outgrowth endothelium as a model of vaso-occlusion and drug testing in sickle cell diseaseUVA Cancer Center Grant RR140081National Science Foundation Graduate Research Fellowship Grant 1650114