Diagnostic Value of Ultrasound in Primary Cervical Ewing's Sarcoma: Two Case Reports and Literature Review

ABSTRACT

Primary cervical Ewing's sarcoma (ES) is a rare malignant small round cell tumor that develops outside the bone, with a generally poor prognosis. Clinical symptoms are nonspecific, posing challenges for early diagnosis. In this report, we present two cases of middle‐aged women presenting with abnormal vaginal bleeding. Neither human papillomavirus typing nor blood tests showed specific abnormalities. Ultrasound examination identified uneven hypoechoic lesions with well‐defined borders in the cervix, and color Doppler imaging showed punctate linear blood flow signals within the lesions. Histopathological biopsies confirmed the diagnosis of primary ES of the uterine cervix. Both patients achieved favorable prognoses following a combined treatment of surgery and chemotherapy. This study highlights the value of ultrasound imaging in aiding the timely diagnosis of this rare malignancy.