Drinking Water Disinfection Byproducts, Ingested Nitrate, and Risk of Endometrial Cancer in Postmenopausal Women

Danielle N. Medgyesi & Mary H. Ward · 2022-05-27

Disinfection byproducts (DBPs) and We investigated the relationship of these exposures with endometrial cancer risk in a large prospective cohort. Among postmenopausal women in the Iowa Women's Health Study cohort, we evaluated two major classes of DBPs, total trihalomethanes (TTHM) and five haloacetic acids (HAA5), and nitrate-nitrogen ( Higher average concentrations of DBPs (95th percentile: TTHM We report novel associations between the highest DBP levels and endometrial cancer for our Iowa cohort that warrant future evaluation. https://doi.org/10.1289/EHP10207.