Development of an HPV 16 rapid test founded in user-centered design with primary care clinicians

Luke P. Brennan & Natalia M. Rodriguez et al. · 2026-01-29

Clinician-informed nucleic acid test for cervical cancer screening to facilitate same-visit results to improve follow-up care.

Links
DOIPubMed
Journal
Analytical Methods
TL;DR

An isothermal nucleic acid amplification platform suitable for outpatient clinics that achieves a clinically relevant limit of detection of 1000 HPV 16 copies per reaction and verifies swabbing technique and test operation with a sample adequacy control.

AI-generated by Semantic Scholar

Institutions
Purdue University West LafayetteIndiana University
Authors
Luke P. Brennan, Francesca Hamacher, Ana L. Claure Dips, Sathveka Sembian, Andrew D. Piepho, Aaron C. Ermel, Jacqueline C. Linnes, Natalia M. Rodriguez
Funding
Community-based Participatory Design of an HPV rapid diagnostic test for cervical cancer screening in South FloridaPoint-of-care screening test for early cervical cancer detectionIndiana Medical Scientist/Engineer Training ProgramCommunity-based Participatory Design of an HPV rapid diagnostic test for cervical cancer screening in South FloridaPoint-of-care screening test for early cervical cancer detectionIndiana Medical Scientist/Engineer Training Program

NCI NIH HHS

K01 CA241073

NCI NIH HHS

R01 CA246315

NIGMS NIH HHS

T32 GM148382

National Cancer Institute

K01CA241073

National Cancer Institute

R01CA246315

National Institute of General Medical Sciences

T32GM148382