Transforming a highly toxic agent DM1 into injectable safe nanomedicines via prodrug self-assembly for the treatment of taxane-resistant cancer

Q: How does OCRA curate its research paper database?

OCRA indexes peer-reviewed papers from PubMed and CrossRef, enriched with MeSH terms, author profiles, and citation metrics. Papers are categorized by cancer type, research method, and clinical relevance.

Q: Can I search papers by MeSH term or author?

Yes. Use the search bar to filter papers by MeSH term, author name, journal, keyword, or cancer type. Each paper includes linked MeSH terms and author profiles for further exploration.

Q: How current is the paper database?

The database is updated regularly through automated ingestion from PubMed and CrossRef. Most papers appear within days of their PubMed indexing date.

doi:10.1039/d3nr00680h

Transforming a highly toxic agent DM1 into injectable safe nanomedicines via prodrug self-assembly for the treatment of taxane-resistant cancer

· 2023-06-15

Through a PUFA strategy, highly toxic DM1 was transformed into a safe self-assemble nanoprodrug, which had low systemic toxicity and could be used to treat taxane-resistant cervical cancer.

Links

DOI PubMed

Journal

Nanoscale

Funding

National Natural Science Foundation of China

22234007

Zhejiang Provincial Outstanding Youth Science Foundation

LR19H160002

Natural Science Foundation of Zhejiang Province

No. LZ17B050001