Phenolato Ti(iv) hexacoordinate complexes for anticancer chemotherapy: enhancement of solubility, hydrolytic stability, and cytotoxicity

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Edit Y. Tshuva

doi:10.1039/d3dt00984j

Phenolato Ti(iv) hexacoordinate complexes for anticancer chemotherapy: enhancement of solubility, hydrolytic stability, and cytotoxicity

Edit Y. Tshuva · 2023-06-06

Five titanium(iv) phenolato complexes were synthesized and fully characterized, and they showed high cytotoxicity, high hydrolytic stability, and enhanced solubility. The halogenated derivatives are identified as the most promising drug candidates.

Phenolato Ti(iv) hexacoordinate complexes for anticancer chemotherapy: enhancement of solubility, hydrolytic stability, and cytotoxicity

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