CRISPR-Cas12a-enhanced mass spectrometric DNA nanomachine for HPV-16 detection in human serum

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Rui Liu; Yi Lv

doi:10.1039/d3cc05949a

CRISPR-Cas12a-enhanced mass spectrometric DNA nanomachine for HPV-16 detection in human serum

Rui Liu & Yi Lv · 2024-01-23

8Citations

Amplified by CRISPR-Cas12a and DNA nanomachines, the sensitive detection of HPV-16 in human serum was performed using mass spectrometry.

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Chemical Communications

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The proposed CRISPR-Cas12a-enhanced mass spectrometric 3D DNA nanomachine for HPV-16 detection in human serum was successfully applied for direct human serum analysis with a low detection limit of 1.2 pM.

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CRISPR-Cas12a-enhanced mass spectrometric DNA nanomachine for HPV-16 detection in human serum

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