A co-formulated vaccine of irradiated cancer cells and cowpea mosaic virus improves ovarian cancer rejection

Zhongchao Zhao & Nicole F. Steinmetz et al. · 2023-06-21

Cowpea mosaic virus adjuvants bind to irradiated cancer cells (ICCs) – the co-delivery of ICCs (the antigen) and CPMV (the adjuvant) demonstrates potent efficacy as a vaccine that protects mice from ovarian tumor challenge.