Highly cytotoxic gold(i)-phosphane dithiocarbamate complexes trigger an ER stress-dependent immune response in ovarian cancer cells

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Hai Van Le; Maria V. Babak; Muhammad Ali Ehsan; Lisa Reichert; Artem L. Gushchin; Wee Han Ang; Anvarhusein A. Isab

doi:10.1039/d0dt01411g

Highly cytotoxic gold(i)-phosphane dithiocarbamate complexes trigger an ER stress-dependent immune response in ovarian cancer cells

Hai Van Le & Anvarhusein A. Isab et al.

Highly cytotoxic Au^I-dithiocarbamate complexes were designed to induce severe integrative stress in ovarian cancer cells, leading to the surface exposure of calreticulin, which is a first step in the activation of immune system.

Highly cytotoxic gold(i)-phosphane dithiocarbamate complexes trigger an ER stress-dependent immune response in ovarian cancer cells

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