Brain metastases in patients with ovarian cancer
Brain metastasis (BM) are uncommon among women with epithelial ovarian cancer (EOC). The frequency, risk factors and clinical repercussions of BM in these patients are not well described. We retrospectively evaluated EOC patients treated at our center from 2002 to 2020 and assessed their clinical parameters, risk for BM development and association with overall survival (OS). This cohort has a known high frequency of BRCA mutation carriers ( Among 1035 EOC patients, 29 (2.8%) were diagnosed with BM. The prevalence of BM are rare among EOC patients. However, the risk is three-fold higher among patients with