Aggressive angiomyxoma: an ultrastructural study update of five cases

Abigail Martínez-Jerónimo & Hugo Domínguez-Malagón et al. · 2025-05-25

The aggressive angiomyxoma (AAM) is a rare mesenchymal tumor known for its locally aggressive behavior and high recurrence rate, predominantly affecting women. Through this analysis of five cases located in the vulva, scrotum, and perineum, the study employs histopathological, immunohistochemical, and ultrastructural techniques to elucidate the tumor's characteristics. Findings revealed confirmatory histopathological and immunohistochemical features. The ultrastructural study details the distinctive features of this entity showing characteristics compatible with myofibroblastic differentiation.