Arf6-mediated macropinocytosis-enhanced suicide gene therapy of C16TAB-condensed Tat/pDNA nanoparticles in ovarian cancer
The cellular uptake of C16TAB-condensed Tat/pDNA nanoparticles (Tat/pDNA/C16TAB, T–P–C) was controlled by Arf6-dependent, Rab-activated macropinocytosis, which promoted T–P–C nanoparticle-based suicide gene therapy of ovarian cancer.
