Investigator
Vice dean/Professor · Tianjin Medical University, School of Pharmacy
Precision-Oriented Theophylline-Platinum(IV) Prodrugs: Eliciting Synthetic Lethality in BRCA1-Deficient Ovarian Cancer with Enhanced Efficacy and Reduced Toxicity In Vitro and In Vivo
Ovarian cancer (OC) is a lethal gynecologic malignancy with limited treatments. Platinum(II) drugs are commonly used but faced severe toxicities and resistance. This study developed theophylline-platinum(IV) prodrugs (
Vice dean/Professor
Tianjin Medical University · School of Pharmacy
PhD
Nankai University · Department of Chemistry
