Impact of the central atom and halido ligand on the structure, antiproliferative activity and selectivity of half-sandwich Ru(ii) and Ir(iii) complexes with a 1,3,4-thiadiazole-based ligand
Cancer cell selective antiproliferative activity of thiadiazole-based half-sandwich complexes in sensitive and resistant ovarian cancer cell lines is triggered by exchanging Ru for Ir and by switching the halido coligand from chloride to iodide.