TL;DR
Given ATF3’s demonstrated capability to downregulate p16 and NF-κB, both of which play important pro-tumorigenic roles in HPV-related CC, ATF3 emerges as a promising therapeutic candidate with the potential for application in the treatment of CC.
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Authors
Zahra Bagheri, Haniyeh Abuei, Alireza Jaafari, Shayan Taki, Amirhossein Akbarpour Arsanjani, Ali Farhadi