Low PPP2R2A expression promotes sensitivity to CHK1 inhibition in high-grade serous ovarian cancer

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doi:10.7150/thno.96879

Low PPP2R2A expression promotes sensitivity to CHK1 inhibition in high-grade serous ovarian cancer

Zhaojun Qiu & Junran Zhang et al. · 2024-11-04

Links

DOI PubMed

Journal

Theranostics

Authors

Zhaojun Qiu, Deepika Singh, Yujie Liu, Chandra B. Prasad, Nichalos Bean, Chunhong Yan, Zaibo Li, Xiaoli Zhang, Goutham Narla, Analisa DiFeo, Qi-En Wang, Junran Zhang

Funding

B55 alpha deficiency as a therapeutic target in cancer Targeting cholesterol metabolism and replication stress response in cancer therapy Exploring potential biomarkers predictive of response to ATR and CHK1 inhibitors

NCI NIH HHS

R01 CA240374

NCI NIH HHS

R01 CA249198

NCI NIH HHS

R21 CA226317