TL;DR
It was found that MK8722 effectively inhibited the malignant biological behaviors of EOC cells, and its target of action, FASN, is a molecular crosstalk between lipid metabolism and autophagy, and exploration of the underlying mechanism of FASn may provide a new research direction.
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Authors
Luhui Wang, Haiyan Zhu, Zhehao Shi, Bo Chen, Huirong Huang, Ganglian Lin, Jiacheng Li, Haitao Yu, Shihao Xu, Gang Chen, Rongying Ou, Chunxiu Dai
