Phosphoproteomics identify arachidonic-acid-regulated signal transduction pathways modulating macrophage functions with implications for ovarian cancer

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doi:10.7150/thno.52442

Phosphoproteomics identify arachidonic-acid-regulated signal transduction pathways modulating macrophage functions with implications for ovarian cancer

Raimund Dietze & Rolf Müller et al. · 2021-01-01

Arachidonic acid (AA) is a polyunsaturated fatty acid present at high concentrations in the ovarian cancer (OC) microenvironment and associated with a poor clinical outcome. In the present study, we have unraveled a potential link between AA and macrophage functions.

Links

DOI PubMed

Journal

Theranostics

Authors

Raimund Dietze, Mohamad K. Hammoud, María Gómez-Serrano, Annika Unger, Tim Bieringer, Florian Finkernagel, Anna M. Sokol, Andrea Nist, Thorsten Stiewe, Silke Reinartz, Viviane Ponath, Christian Preußer, Elke Pogge von Strandmann, Sabine Müller-Brüsselbach, Johannes Graumann, Rolf Müller