Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer

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doi:10.7150/thno.30736

Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer

Brittney S. Harrington & John D Hooper et al. · 2020-01-12

CUB-domain containing protein 1 (CDCP1) is a cancer associated cell surface protein that amplifies pro-tumorigenic signalling by other receptors including EGFR and HER2. Its potential as a cancer target is supported by studies showing that anti-CDCP1 antibodies inhibit cell migration and survival

Links

DOI PubMed

Journal

Theranostics

Authors

Brittney S. Harrington, Yaowu He, Tashbib Khan, Simon Puttick, Paul J. Conroy, Thomas Kryza, Tahleesa Cuda, Kamil A Sokolowski, Brian WC Tse, Katherine K. Robbins, Buddhika J. Arachchige, Samantha J. Stehbens, Pamela M. Pollock, Sarah Reed, S. John Weroha, Paul Haluska, Carlos Salomon, Rohan Lourie, Lewis C. Perrin, Ruby H. P. Law, James C. Whisstock, John D Hooper