Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability

· 2020-08-18

Loss of DNA demethylase TET2 protects stalled replication forks from degradation and confers chemoresistance.

Funding

Intramural NIH HHS

ZIA BC010387

Intramural NIH HHS

ZIA BC011311

NCI, NIH Intramural Program

Department of Defense, Breast Cancer Research Program

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