Constitutive expression of progesterone receptor isoforms promotes the development of hormone-dependent ovarian neoplasms

Margeaux Wetendorf & Francesco J. DeMayo et al. · 2020-10-06

Altering the relative abundance of progesterone receptor isoforms drives ovarian neoplasia in mice.

Links
DOIPubMed
Journal
Science Signaling
Institutions
National Institute Of Environmental Health SciencesXinjiang Medical UniversityHuazhong University Of Science And TechnologyDan L Duncan Comprehensive Cancer CenterIntegrated Laboratory Systems IncUniversit De Montral
Authors
Margeaux Wetendorf, Rong Li, San-Pin Wu, Jian Liu, Chad J. Creighton, Tianyuan Wang, Kyathanahalli S. Janardhan, Cynthia J. Willson, Bruce D. Murphy, Francesco J. DeMayo
Funding
Developmental Biology of Neural DiseasesNuclear Receptors and Coregulators in Health and DiseasePROJECT 1 - Endometrial Steroid Receptor Coregulator-2 in Peri-Implantation BioloTumor BiologyMolecular Analysis of Uterine ReceptivityEnvironmental Signaling in Reproduction and PregnancyCORE--CELL AND ORGAN CULTURENational Cancer Institute Grant CA125123PROJECT 1 - Endometrial Steroid Receptor Coregulator-2 in Peri-Implantation BioloNational Institute of Environmental Health Sciences Grant Z1AES103311Molecular Analysis of Uterine ReceptivityPROJECT 1 - Endometrial Steroid Receptor Coregulator-2 in Peri-Implantation BioloCanadian Institutes of Health Research Grant 125936

NICHD NIH HHS

T32 HD007495

NIDDK NIH HHS

U19 DK062434

NICHD NIH HHS

U54 HD007495

NCI NIH HHS

P30 CA125123

NICHD NIH HHS

R01 HD042311

Intramural NIH HHS

ZIA ES103311

NICHD NIH HHS

P30 HD007495

National Institute of Diabetes and Digestive and Kidney Diseases

U54HD007495

Eunice Kennedy Shriver National Institute of Child Health and Human Development

HD042311

Eunice Kennedy Shriver National Institute of Child Health and Human Development

U54HD007495