Functional proteomics interrogation of the kinome identifies MRCKA as a therapeutic target in high-grade serous ovarian carcinoma

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Alison M. Kurimchak; Jennifer Brown; Vikas Kumar; Shane O’Brien; Jonathan Chernoff; James S. Duncan

doi:10.1126/scisignal.aax8238

Functional proteomics interrogation of the kinome identifies MRCKA as a therapeutic target in high-grade serous ovarian carcinoma

Alison M. Kurimchak & James S. Duncan et al. · 2020-02-18

Kinome profiling of ovarian tumors reveals a way to treat patients and get a step ahead of drug resistance.

Funding

NCI NIH HHS

P30 CA006927

NCI NIH HHS

R01 CA142928

NCI NIH HHS

R01 CA211670

NCI NIH HHS

T32 CA009035

National Institutes of Health

CA06927

American Cancer Society

IRG-92-027-20

National Cancer Institute

CA211670

National Cancer Institute

CA142928

National Cancer Institute

CA009035

Functional proteomics interrogation of the kinome identifies MRCKA as a therapeutic target in high-grade serous ovarian carcinoma

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