Transgelin 2 guards T cell lipid metabolism and antitumour function

Sung-Min Hwang & Juan R. Cubillos-Ruiz et al. · 2024-10-23

Mounting effective immunity against pathogens and tumours relies on the successful metabolic programming of T cells by extracellular fatty acids
Links
DOIPubMed
Journal
Nature
Institutions
Weill Cornell MedicineNew York Medical CollegeUnknown InstitutionMoffitt Cancer CenterStony Brook UniversityUniversity Of HelsinkiSungkyunkwan University
Authors
Sung-Min Hwang, Tito A. Sandoval, Bikash Mishra, Lionel B. Ivashkiv, Jose Conejo-Garcia, Martin Kaczocha, Anna Vähärautio, Minkyung Song, Juan R. Cubillos-Ruiz
Funding
Immunometabolic Programs Controlled by ER Stress in CancerDevelopment of the Next Generation of FABP5 Inhibitors to Treat Prostate CancerImmunosuppressive Programs Driven by IRE1 signaling in ovarian cancerPathologyDevelopmental FundsCytokine Balance in Rheumatoid ArthritisBile acids restrict functional reprogramming of myeloid-derived suppressor cells in tumor bedsPOTENTIATION OF ANTI-TUMOR IMMUNITY BY ONCOLYTIC VIRUS IN SITU VACCINATIONTriple Quadrupole - Ion Trap Hybrid LC/MS/MS SystemMitochondrial stress promotes immunosuppressive potential of myeloid subsets in tumorsLinear Ion Trap - Quadrupole LC-MS SystemEndoplasmic Reticulum Stress Responses in PainER stress-driven IRE1a-XBP1 signaling in lung cancer

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