Triage performance of PAX1m/JAM3m in opportunistic cervical cancer screening of non‒16/18 human papillomavirus-positive women: a multicenter prospective study in China

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doi:10.1186/s13148-024-01731-w

Triage performance of PAX1m/JAM3m in opportunistic cervical cancer screening of non‒16/18 human papillomavirus-positive women: a multicenter prospective study in China

Xiaojing Chen & Lei Li et al. · 2024-08-16

In this study, we aimed to validate the performance of the PAX1 and JAM3 methylation (PAX1 The triage performance of liquid-based cytology (LBC) and the PAX1 In total, 1851 participants had cervical histological outcomes and were included in the analysis. The sensitivity/specificity of the LBC test results with atypical squamous cells of undetermined significance or worse (LBC ≥ ASCUS) and the PAX1 In non-16/18 hrHPV(+) women, PAX1

Links

DOI PubMed

Journal

Clinical Epigenetics

Authors

Xiaojing Chen, Xitong Jin, Linghua Kong, Yuligh Liou, Pei Liu, Zhe Dong, Sijun Zhou, Bingli Qi, Jing Fei, Xiaoyan Chen, Guangwu Xiong, Yuchong Hu, Shikai Liu, Jianwei Zhou, Huafeng Shou, Lei Li

Funding

State Key Laboratory for Complex, Severe and Rare Diseases in Peking Union Medical College Hospital, by the Beijing Science and Technology Projects Grant Z211100002921068 the Key Research Project of Beijing Natural Science Foundation Grant Z220013 the CAMS Innovation Fund for Medical Sciences (CIFMS) Grant 2022-I2M-C&T-B-033 the National High Level Hospital Clinical Research Funding Grant 2022-PUMCH-A-117, 2022-PUMCH-B-083, 2022-PUMCH-C-010, 2022-PUMCH-C-022 and 2022-PUMCH-D-003 China Postdoctoral Science Foundation Grant 2022T150066 the CAMS Innovation Fund for Medical Sciences Grant 2022-I2M-C&T-B-033