TL;DR
It is demonstrated that GATA4 suppresses lysosomal acidification and epithelial–mesenchymal transition, while its CRL4B-mediated ubiquitination and degradation in metastatic ovarian cancer cells leads to reduced H3K27ac modification at tumor suppressing genes.
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Authors
Xin Yin, Rufei Gao, Yanqing Geng, Xinyi Mu, Yan Zhang, Yidan Ma, Xuemei Chen, Fei Han, Zhuxiu Chen, Fangfang Li, Junlin He
