Simultaneously delivery of functional gallium ions and hydrogen sulfide to endow potentiated treatment efficacy in chemo- and PARPi-resistant ovarian cancer

Sangsang Tang & Junfen Xu et al. · 2025-02-01

4Citations
Limited therapeutic options are available for patients with platinum-resistant ovarian cancer (OC). Herein, we developed gallium sulfide-embedded bovine serum albumin nanoformulations (Ga
Links
DOIPubMed
Journal
Journal of Nanobiotechnology
TL;DR

Gallium sulfide-embedded bovine serum albumin nanoformulations (Ga2S3-BSA NMs) demonstrated a potentially safe and practical strategy by using Ga2S3-BSA NMs to combat drug resistance in platinum-resistant OC.

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Authors
Sangsang Tang, Yangyang Li, Yifeng Fang, Mengyan Tu, Shenglong Wu, Yixuan Cen, Junfen Xu
Funding
National Natural Science Foundation of China Grant 82472891Key Program of Zhejiang Province Natural Science Foundation of China Grant LZ24H160001Medical Interdisciplinary Innovation Program 2024, Zhejiang University School of Medicine Funding