A prognostic model based on immune cells in tumor microenvironment to predict prognosis in endometrial cancer

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doi:10.1186/s12885-025-15392-2

The interaction between the tumor immune microenvironment (TIME) and malignant tumor cells plays a crucial role in tumor initiation and progression. This study aimed to establish and validate a prognostic model based on TIME characteristics to predict prognosis and guide personalized treatment in patients with endometrial cancer (EC). A total of 67 EC patients who underwent surgery and TIME profiling at Peking University People's Hospital between January 2018 and December 2022 were included in this study. A prognostic model was developed based on the densities of stroma CD3 (1) Multiplex immunofluorescence (mIF) analysis of the 67 EC patients revealed significant differences between the Recurrence and Non-Recurrence groups in the densities of stroma PD-L1 This study identified two immune cell types-Stroma CD3

A prognostic model based on immune cells in tumor microenvironment to predict prognosis in endometrial cancer

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