High-dose-rate brachytherapy using inverse planning optimization with tandem and ovoid applicators for locally advanced cervical cancer: a simulation study

Yuji Yaegashi · 2021-06-02

1Citations
The purpose of this study was to evaluate the dosimetric advantage of inverse planning optimization (IPO) in locally advanced cervical cancer using high-dose-rate (HDR) brachytherapy (BT). IPO was compared with point A plan and geometric optimization (GO). The three planning methods were evaluated using doses to the virtual organ-at-risk (OAR) and D90 (the minimum dose covering of 90% of the volume) to the virtual high-risk clinical target volume (HR-CTV) based on quantitative analysis. HR-CTV structures measuring 38.5 cm
TL;DR

Investigating the dosimetric advantage of inverse planning optimization in locally advanced cervical cancer using high-dose-rate (HDR) brachytherapy (BT) compared with point A plan and geometric optimization (GO) found that IPO makes it possible to deliver a sufficient dose for the D90 of the HR-CTV while reducing OAR doses with smallerHR-CTV values.

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