A randomized clinical trial assessing the efficacy of vitamin B prophylaxis in attenuating paclitaxel-induced neuropathy and the imperative use of gabapentin in diabetic ovarian cancer patients

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doi:10.1007/s12032-026-03252-3

A randomized clinical trial assessing the efficacy of vitamin B prophylaxis in attenuating paclitaxel-induced neuropathy and the imperative use of gabapentin in diabetic ovarian cancer patients

Mahitab Haggagy & Hanan Nassar et al. · 2026-02-06

Links

DOI PubMed

Journal

Medical Oncology

TL;DR

This study showed a significant reduction in CIPN grade over time, with fewer patients progressed to higher grades in prophylactic versus non-prophylactic group, extended to significant improvement in CIPN in prophylactic versus non-prophylactic diabetic patients.

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Authors

Mahitab Haggagy, Fatma Raslan, Norhan El Said, Shahenda Ghaly, Hanan Nassar