Extracellular vesicles derived from M2-polarized tumor-associated macrophages promote immune escape in ovarian cancer through NEAT1/miR-101-3p/ZEB1/PD-L1 axis

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Yu Wang

doi:10.1007/s00262-022-03305-2

Extracellular vesicles derived from M2-polarized tumor-associated macrophages promote immune escape in ovarian cancer through NEAT1/miR-101-3p/ZEB1/PD-L1 axis

Yu Wang · 2022-11-01

35Citations

Evidence has been presented demonstrating that CD8

Links

DOI PubMed

Journal

Cancer Immunology, Immunotherapy

TL;DR

In vitro and in vivo assays confirmed the tumor-supporting effects of NEAT1 delivered by M2-derived EVs on OC cell proliferation and CD8^+ T cell apoptosis as well as tumor growth.

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Institutions

Heilongjiang University Of Chinese Medicine

Authors

Yu Wang