The role of 18F-FDG-PET/CT in predicting the histopathological response in locally advanced cervical carcinoma treated by chemo-radiotherapy followed by radical surgery: a prospective study

Vittoria Rufini & Alessandro Giordano et al. · 2019-08-14

This prospective study aimed to evaluate whether Between October 2010 and June 2014, 88 patients with LACC were enrolled. For each patient, three At histopathology, 40 patients had complete response (CR, pR0), 48 had partial response (PR: 21 microscopic [pR1] and 27 macroscopic [pR2]). At baseline, SUV In LACC patients treated with CRT followed by surgery, early variations in metabolic parameters effectively discriminate histopathological PR of the primary tumor, suggesting the potential role of
Authors
Vittoria Rufini, Angela Collarino, Maria Lucia Calcagni, Guido Maria Meduri, Valentina Fuoco, Tina Pasciuto, Antonia Carla Testa, Gabriella Ferrandina, Maria Antonietta Gambacorta, Maura Campitelli, Benedetta Gui, Gianfranco Zannoni, Riccardo Manfredi, Giovanni Scambia, Alessandro Giordano