Mediastinal Recurrence of Uterine Cervix Cancer on 18F-FDG PET/CT

Abstract

We report the case of a 64-year-old woman with a mediastinal relapse of a uterine cervix cancer with positive human papillomavirus, an unusual site of recurrence. She consulted because of solid and liquid dysphagia of sudden appearance. Endoscopic study and non–contrast-enhanced CT showed intraluminal esophageal stenosis with a retrograde esophageal distension. ¹⁸F-FDG PET/CT demonstrated an infiltrating hypermetabolic lesion in posterior mediastinum, middle and lower esophagus, and stomach, with no signs of local or regional relapse of the uterine neoplasm.