Evaluating Radiotheranostic Targets for Endometrial Cancer

Joni Sebastiano & Brian M. Zeglis et al. · 2025-10-01

Endometrial cancer is the most common gynecologic malignancy worldwide, and its incidence and mortality rates have increased over the past decade. Although early-stage disease is effectively treated via hysterectomy, a dearth of molecularly targeted therapies means that prognoses are far poorer for those with disseminated or recurrent disease. Herein, we describe the exploration of 3 biomarkers-human epidermal growth factor receptor 2 (HER2), mucin-16 (MUC16), and CD24-as potential radiotheranostic targets for endometrial cancer.
Authors
Joni Sebastiano, Shane A. McGlone, Zachary V. Samuels, Camilla Grimaldi, Ava Stoddard, Sugar Galka, Emma Colaco, Brian M. Zeglis