Interrogating the Theranostic Capacity of a MUC16-Targeted Antibody for Ovarian Cancer

Q: How does OCRA curate its research paper database?

OCRA indexes peer-reviewed papers from PubMed and CrossRef, enriched with MeSH terms, author profiles, and citation metrics. Papers are categorized by cancer type, research method, and clinical relevance.

Q: Can I search papers by MeSH term or author?

Yes. Use the search bar to filter papers by MeSH term, author name, journal, keyword, or cancer type. Each paper includes linked MeSH terms and author profiles for further exploration.

Q: How current is the paper database?

The database is updated regularly through automated ingestion from PubMed and CrossRef. Most papers appear within days of their PubMed indexing date.

doi:10.2967/jnumed.123.266524

Interrogating the Theranostic Capacity of a MUC16-Targeted Antibody for Ovarian Cancer

Kyeara N. Mack & Jason S. Lewis et al. · 2024-04-01

Aberrantly expressed glycans on mucins such as mucin-16 (MUC16) are implicated in the biology that promotes ovarian cancer (OC) malignancy. Here, we investigated the theranostic potential of a humanized antibody, huAR9.6, targeting fully glycosylated and hypoglycosylated MUC16 isoforms.

Links

DOI PubMed

Journal

Journal of Nuclear Medicine

Authors

Kyeara N. Mack, Zachary V. Samuels, Lukas M. Carter, Tara D. Viray, Komal Mandleywala, Cory L. Brooks, Michael A. Hollingsworth, Prakash Radhakrishnan, Jason S. Lewis

Funding

Pathology

NCI NIH HHS

P30 CA008748