Prioritizing the risk of cervical cancer: findings from the SCCUT Multicentre Initiative
Cervical cancer (CC) remains a significant global health burden, ranking eighth in incidence and ninth in cancer-related mortality among women worldwide. Persistent infection with high-risk human papillomavirus (HPVhr) is the primary etiological factor in CC development. The SCCUT program in Romania was designed to enhance access to primary screening and assess HPVhr prevalence among women aged 25-65 years in the South-Muntenia region. Between August 2022 and November 2023, a total of 36,813 women were enrolled in the SCCUT program after providing informed consent. Based on age, participants underwent either a Pap test and/or HPVhr testing. Clinical and demographic data-including age, hormonal status, intrauterine device (IUD) use, presence of leucorrhea, and history of cervical interventions-were collected via structured questionnaires. HPVhr testing was performed using the AmpFire