Homologous recombination deficiency in high-grade serous ovarian carcinoma: clinical pathological characteristics, impact of neoadjuvant chemotherapy, and prognostic implications

Yunjie Ge & Ping-Li Sun et al. · 2026-02-09

TL;DR

HRD status is a prognostic biomarker in HGSC and its correlation with SET patterns supports histology as an initial screening tool, underscoring the need for HRD testing before chemotherapy to ensure accurate assessment and guide treatment.

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