Night shift work, sleep duration and endometrial cancer risk: A pooled analysis from the Epidemiology of Endometrial Cancer Consortium (E2C2)
Data on the role of circadian related factors in the etiology of endometrial cancer are scarce. We collected individual data on night shift work or daily sleep duration from 7,207 cases and 22,027 controls participating in 11 studies from the Epidemiology of Endometrial Cancer Consortium (E2C2). Main analyses were performed among postmenopausal women: 6,335 endometrial cancer cases and 18,453 controls. Using individual data, study-specific odd ratios (ORs) and their corresponding 95% confidence intervals (CIs) were estimated with logistic regression and pooled analyses were conducted using random-effects meta-analyses. A non-significant inverse association was observed between endometrial cancer and night shift work (OR=0.89, 95%CI=0.72-1.09; I
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Sleep Medicine ReviewsInstitutions
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NCI NIH HHS Grant HHSN261201800032CCore A: Biospecimen and High-Dimensional Data Management CoreComprehensive molecular characterization of endometrial cancer, etiologic heterogeneity, and racial disparitiesCollaborative Genetic Study of Ovarian Cancer RiskNCI NIH HHS Grant HHSN261201800015IMolecular Epidemiology of Endometrial CancerENDOMETRIAL CANCER RISK AND POSTMENOPAUSAL HORMONE USEESTROGEN, DIET, GENETICS AND ENDOMETRIAL CANCERMolecular Epidemiology of Nutrition and Cancer in the Multiethnic Cohort StudyNCI NIH HHS Grant HHSN261201800032IBREAST CANCER AND THE BIRTH CONTROL PILL-275923166NCI NIH HHS Grant HHSN261201800009IInnovative Infrastructure to Enhance and Sustain the California Teachers Study CohortNew Biospecimens to Enhance Research in the California Teachers Study CohortNCI NIH HHS Grant HHSN261201800009CMentoring and Research in Cancer EpidemiologyNCCDPHP CDC HHS Grant NU58DP006344Epidemiology of Ovarian Cancer:New HypothesesMolecular Pathoepidemiology of Endometrial Cancer RiskPathologyType 1 and Type 2 Endometrial Cancer: Have They Different Risk Factors? A PooledHormone-Related CancersSpecialized Cancer Center Support GrantRole of Genetic and Lifestyle Interplay in Uterus CancerBreast and Other Cancers in the California Teachers CohortLeadership, Planning and EvaluationHormone-Related CancersNCI NIH HHS Grant HHSN261201800015CSouthern Community Cohort StudyCancer Biology Research ProgramUnderstanding Population Differences in Cancer: The MEC Study