Evaluating photodynamic therapy protocols for high-grade cervical neoplasia: A comparative study
1Citations
Cervical cancer has the infection by the Human Papillomavirus (HPV) as one of the main conditions for its development. Photodynamic Therapy (PDT) is a non-invasive treatment that combines the interaction between oxygen, light, and a photosensitizing molecule, resulting in cellular damage. HPV - infected cells because they are metabolically more active, can be better affected by this technique, promoting an alternative topic treatment for Cervical Intraepithelial Lesions (CIN). The present prospective and randomized study compared three PDT protocols applied to 31 patients with high-grade CIN and infected by HPV. Protocols used LEDs with a wavelength of 630 nm and a fluence of 150 J/cm