Hysteroscopy in Asymptomatic Postmenopausal Women With Thickened Endometrium: Analyzing Clinical Characteristics and Pathology With an Emphasis on SERM History

Jiali Tong · 2025-08-16

1Citations
To optimize cut-off values of endometrial thickness for referral to hysteroscopy among asymptomatic postmenopausal women with thickened endometrium. A retrospective observational analysis. A teaching hospital. 415 asymptomatic postmenopausal cases who underwent hysteroscopy with thickened endometrium between January 2014 to January 2023. Patients with endometrium thicker than 5mm underwent hysteroscopy for endometrial pathological examination. Transvaginal sonography (TVS) reports of 37732 patients who had ET ≥ 5mm were reviewed. Among them, 415 patients were postmenopausal and asymptomatic. Their clinical characteristics were analyzed retrospectively, including demographic data, TVS reports, hysteroscopy surgery records, and pathology results. Endometrial thickness significantly differed between patients whose samples were pathologically benign and those who turned out premalignant or malignant (χ Increasing the endometrial thickness cut-off value in asymptomatic postmenopausal women, especially for those with a history of SERM treatment, would improve patient management.
TL;DR

Increasing the endometrial thickness cut-off value in asymptomatic postmenopausal women, especially for those with a history of SERM treatment, would improve patient management.

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