Metal (Au, Pt, Pd, Ni) Bis(dithiolene) complexes as dual-action agents combating cancer and trypanosomatid infections

Hadi Hachem & Fernanda Marques et al. · 2024-11-29

Cancer and infection diseases pose severe threats to public health worldwide stressing the need for more effective and efficient treatments. Thus, the search for broad-spectrum activity drugs seems justifiable and urgent. Herein, we investigate the anticancer and antitrypanosomatid (anti-Trypanosoma cruzi) activities of eight monoanionic metal bis(dithiolene) complexes, [Ph
Authors
Hadi Hachem, Yann Le Gal, Olivier Jeannin, Dominique Lorcy, Gonzalo Scalese, Leticia Pérez-Díaz, Dinorah Gambino, António P. Matos, Fernanda Marques