Unlocking the potential of iridium and ruthenium arene complexes as anti-tumor and anti-metastasis chemotherapeutic agents

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doi:10.1016/j.jinorgbio.2022.112057

Unlocking the potential of iridium and ruthenium arene complexes as anti-tumor and anti-metastasis chemotherapeutic agents

Mengdi Lv & Hong-Ke Liu et al. · 2022-11-02

It is a major challenge to design novel multifunctional metal-based chemotherapeutic agents for anti-tumor and anti-metastasis applications. Two complexes (OA-Ir and OA-Ru) were synthesized via CuAAC (copper-catalyzed azide-alkyne cycloaddition) reaction from nontoxic Ir-N

Links

DOI PubMed

Journal

Journal of Inorganic Biochemistry

Authors

Mengdi Lv, Xiaoting Qian, Shijie Li, Jie Gong, Qun Wang, Yong Qian, Zhi Su, Xuling Xue, Hong-Ke Liu

Funding

National Natural Science Foundation of China Grant 21420102002 National Natural Science Foundation of China Grant 21771109 National Natural Science Foundation of China Grant 21807060 National Natural Science Foundation of China Grant 22077066