Quercetin alleviates imatinib-induced premature ovarian insufficiency by regulating mitophagy via the ROS/JNK/c-JUN pathway

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This study employed an integrated approach combining network pharmacology with in vivo and in vitro experiments to demonstrate whether IMA induces excessive oxidative stress and mitophagy in ovarian granulosa cells, and further determine whether QUE exerts its protective effects through this pathway.

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