Postoperative Adjuvant Treatments for Cervical Cancer: A Network Meta-Analysis
This study aimed to perform a comprehensive network meta-analysis assessing the efficacy and safety of 5 postoperative adjuvant therapies (PATs) for early-stage cervical cancer, comparing their effects on survival and adverse outcomes to identify the therapy with the most significant survival benefit. We comprehensively searched PubMed, Web of Science, the Cochrane Library, Embase, CNKI, VIP, Wanfang, and CBM for randomized controlled trials on PATs-including concurrent chemoradiation therapy (CCRT), radiation therapy (RT), chemotherapy (CT), sequential chemoradiation therapy (SCRT), and CCRT followed by consolidation chemotherapy (CCRT + CT)-in patients with cervical cancer from inception to October 2024. Study bias was assessed with the Cochrane ROB.2. A Bayesian random-effects network meta-analysis was conducted for indirect comparisons, with τ