Thermoradiotherapy Optimization Strategies Accounting for Hyperthermia Delivery Uncertainties

Timoteo D. Herrera · 2024-07-15

The combined effect of hyperthermia and radiation therapy can be quantified by an enhanced equivalent radiation dose (EQD Using Plan2Heat, we computed preplanning hyperthermia plans and treatment adjustment scenarios for 3 cervical cancer patients. We imported these scenarios into RayStation 12A for optimization with 4 different strategies: (1) conventional radiation therapy optimization prescribing 46 Gy to the planning target volume (PTV), (2) nominal EQD EQD EQD