The radiosensitization effect of hyperthermia can be considered and quantified as an enhanced equivalent radiation dose (EQD Biological modeling was performed using our in-house developed software (X-Term), considering a 23- × 2-Gy external beam radiation scheme, as applied for patients with locally advanced cervical cancer. First, the EQD EQD Biological modeling provides relevant insight into the relationship between treatment parameters and expected EQD