Atranorin from lichens act as potential inhibitor for cervical tumor proteins TGFbeta and kinase enzyme CDK4/CyclinD3: An anti-cancer intervention therapy
In the present study a potential anticancer compound atranorin was identified and isolated from the foliose lichen Heterodermia boryi. The study also evaluated the pharmacological potential of the foliose lichens Sticta weigelii and Heterodermia boryi against cervical cancer. Qualitative analysis of phytochemicals revealed the presence of alkaloids, flavonoids, phenolics, terpenoids and tannin compounds in both lichens. Saponins and glycosides are present only in S. weigelii. The presence of atranorin in H. boryi was confirmed by HPTLC, and its structure was elucidated by