Immunomodulatory and anti-ovarian cancer effects of novel astragalus polysaccharide micelles loaded with podophyllotoxin

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doi:10.1016/j.ijbiomac.2024.138960

Immunomodulatory and anti-ovarian cancer effects of novel astragalus polysaccharide micelles loaded with podophyllotoxin

Mo Liu & Xue-tao Li et al. · 2024-12-19

Ovarian cancer, a highly lethal form of gynecological cancer globally, has witnessed notable advancements in its treatment through the integration of nanotechnology and immunotherapy. Here, we designed a novel astragalus polysaccharide vector (PDA), encapsulating podophyllotoxin (PPT), and modifying methotrexate (DSPE-PEG

Links

DOI PubMed

Journal

International Journal of Biological Macromolecules

Authors

Mo Liu, Zi-xu Zhang, Jia-hua Wang, Rui-bo Guo, Lu Zhang, Liang Kong, Yang Yu, Juan Zang, Yang Liu, Xue-tao Li